Pyrimidine, 2-chloro-4-ethynyl- - Names and Identifiers
Pyrimidine, 2-chloro-4-ethynyl- - Physico-chemical Properties
| Molecular Formula | C6H3ClN2
|
| Molar Mass | 138.55 |
| Density | 1.32±0.1 g/cm3(Predicted) |
| Melting Point | 139-141 °C |
| Boling Point | 272.1±13.0 °C(Predicted) |
| pKa | -2.67±0.20(Predicted) |
Pyrimidine, 2-chloro-4-ethynyl- - Upstream Downstream Industry
Pyrimidine, 2-chloro-4-ethynyl- - Introduction
Pyrimidine, 2-chloro-4-ethynyl- (9CI), also known as Cyborg (9CI), is an organic compound. Its molecular formula is C6H3ClN2, relative molecular mass is 144.56g/mol.
Pyrimidine, 2-chloroo-4-ethynyl- (9CI) is a white crystalline solid with special chemical properties and some important applications. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: 76-77 ° C
-Boiling point: 210 ° C
-has a strong odor
Use:
- Pyrimidine, 2-chloroo-4-ethynyl- (9CI) can be used as an important intermediate in organic synthesis and can be used to prepare other compounds, such as pesticides, drugs and dyes.
-It is also often used as a nucleobase mimetic for DNA or RNA synthesis and as a raw material for anticancer drug research.
Method:
The preparation of-Pyrimidine, 2-chloroo-4-ethynyl- (9CI) can be obtained by reacting 2,4-dichloropyrimidine with triethynyl borate under alkaline conditions.
Safety Information:
- Pyrimidine, 2-chloro-4-ethynyl- (9CI) need to pay attention to its protective measures when using and storing, avoid contact with skin and inhalation.
-It is irritating and toxic and may cause damage to the eyes, skin and respiratory system.
-During use, pay attention to safe operation to avoid dust or harmful gases due to high temperature.
-Wear personal protective equipment when handling the compound and observe chemical safety practices.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 19:05:55